Erectile dysfunction endocrine genesis is actually a rare variant, up to 5% of all cases of erectile dysfunction. It should be distinguished from psychogenic from organic as well as such emerging due to loss of vital condition occurring during long-term medical condition. Erectile dysfunction endocrine genesis can be divided into four broad categories:
Erectile dysfunction in cases of hypogonadism, i.e. conditions characterized by decreased secretion of testosterone;
Erectile dysfunction in states of hiperestrogenizam;
Erectile dysfunction in hyperprolactinemias;
Erectile dysfunction common endocrinopathies.
Five common endocrinopathies can lead to disorders in sexuality: acromegaly, hypothyroidism, hyperthyroidism, hypocorticism and hypercortisolism.
Erectile dysfunction in cases of hypogonadism
Testosterone has been shown necessary for the formation and promotion of male sexual behavior. By contrast, however, in already established sexual behavior, testosterone plays only a partial role in its maintenance. A shortage of testosterone:
diluted automatic erections;
not modify however significant mental erections;
causes a delay in ejaculation;
leads to a reduction in the volume of ejaculate.
The effect of testosterone on sexuality is proportional to the level in the circulating blood. Normally, it is between 2 and 4.5 ng / ml in different individuals. Sexual activity increases the secretion of testosterone. Testosterone circulates in the blood bound to a large part with various proteins, among which the most specific binding protein is sex. Only the remaining unbound (free) part is able to exert biological effects.
There is no physiological menopause. As we age there is a progressive and relatively parallel reduction of the levels of free testosterone and global. However, there is a rise in age-sex binding protein'a, which to some extent determines the faster decrease in free testosterone, which is biologically active against global one.